Yeast pheromone response model
From Yeast Pheromone Model
Contents |
Reactions
Receptor/G-Protein
Pheromone/Receptor/G protein interactions
G protein nucleotide hydrolysis/exchange
RGS(Sst2)/Galpha(Gpa1)/Receptor(Ste2) interactions
Gβ(Ste4)/Gγ(Ste18) interaction
Synthesis/Degradation
Receptor(Ste2) synthesis/endocytosis/degradation
RGS(Sst2) synthesis/degradation
Gα(Gpa1) synthesis/degradation
MAPK Cascade
Ste4:Ste18/Ste5 interactions and Ste5 dimerization/oligomerization
Ste5/MAPK cascade interactions
Synthesis/Degradation
Gene Expression
Dig1/Dig2/Ste12/Tec1 interactions
Dig1/Dig2/Ste12 phosphorylation
Ste12 mediated protein synthesis
Synthesis/Degradation
Tec1 synthesis/degradation
Ste12 synthesis/degradation
Other
Non-specific dephosphorylation
Protein dilution/synthesis due to cell growth
Cell cycle regulation of pheromone response
Pheromone-dependent cell cycle arrest
Parameter Constraint Assumption Pages
MAPK/target interaction properties
Gpa1/Ste4 binding and nucleotide hydrolysis/exchange rate constant constraints
Ste2/Gpa1/Ste4:Ste18 binding rate constant constraints
Ste5 dimerization and Ste4 binding rate constant constraints
Dig1/Dig2/Ste12/MAPK binding rate constant constraints
Elemental Species
Cell
Dig1
Dig2
Far1
Fus3
Gpa1
Kss1
Msg5
Pheromone
Ptp2/Ptp3
Sst2
Ste2
Ste4:Ste18
Ste5
Ste7
Ste11
Ste12
Ste20
Yck
Species not included in model
Bem1
Bni1
Cdc24
Cdc28
Cdc42
Fus1
Hog1
Pbs2
Prm1
Spa2
Ste50
Tec1
Phenomenology
Page Categories
Yeast Pheromone Response Model
Reactions - Yeast Pheromone Response Model
Parameters - Yeast Pheromone Response Model
Species - Yeast Pheromone Response Model