MAPK pY only Kd factor

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MAPK_pY_only_Kd_factor = 2


Definition

This is the factor by which phosphorylation of Fus3 or Kss1 on just the tyrosine decreases its affinity for a target, compared to the affinity of doubly phosphorylated Fus3 or Kss1 for that same target.
Kd_MAPKpY_target = MAPK_pY_only_Kd_factor * Kd_MAPKpTpY_target
MAPK_pY_only_Kd_factor > 1 means that MAPKpY binds its targets more weakly than MAPKpTpY.

Source

  • Experimentally measured for ERK2 phosphorylation of MBP and ELK1.

Trust

  • Medium

Additional Details

See MAPK/target interaction properties for more details.

Retrieved from "http://yeastpheromonemodel.org/wiki/MAPK_pY_only_Kd_factor"
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